Martha Lyle, fourth child of Matthew Lyle and his wife, Esther Blair, was born about 1740. She accompanied her parents from Ireland to Virginia and married there about 1758, Matthew Houston, son of John Houston and an uncle to General Samuel Houston.
Their children were John (who married Rachel Balch); Samuel (who married Nancy Gillespie, married second Mary Mitchell, by whom he had no children, and married third Annie Hutchison, by whom he had no children); Matthew (who married Margaret Cloyd); Robert D., (who died unmarried); Esther (who married her cousin, Major James Houston); and Margaret (who married Captain James Gillespie).