Whitinsville is an unincorporated village within the town of Northbridge in Worcester County, Massachusetts, United States. Whitinsville is a census-designated place (CDP) and its population was 6,704 at the 2010 census. Whitinsville is pronounced as if it were spelled "White-ins-ville". It was founded by the Whitin family, after whom it is also named. It is a post office jurisdiction, with a zip code of 01588. It is located on the Mumford River, a tributary of the Blackstone River.
Whitinsville has been designated as a mill village of national historic significance to America's earliest industrialization, and is one of only four villages selected by the John H. Chaffee Blackstone River Valley National Historic Corridor Commission to receive this designation. Hopedale is the only other Massachusetts mill village to achieve this designation by the corridor commission.