The I Tarapacá Region is one of Chile's 15 first order administrative divisions. It borders the Chilean Arica and Parinacota Region to the north, Bolivia's Oruro Department on the east, the Antofagasta Region on the south and the Pacific Ocean on the west. The port city of Iquique (2002 pop. 216,419) is the region's capital.
Much of the region was once the Tarapacá Province of Peru, which was annexed by Chile under the 1883 Treaty of Ancón at the close of the War of the Pacific. The region was important economically as a site of intense saltpeter mining, before synthetic nitrate manufacturing became possible. A number of abandoned mining towns can still be found in the region.