Person:Diego Colón Y Pravia (1)

2nd Duke of Veragua, 4th Admiral of the Indies, Marquis of Jamaica -- LAST DIRECT MALE DESCENDANT OF THE DISCOVERER

Diego was one of the first students at the monastery that became the University of Santo Domingo. He lived at Gelves in 1572 with his cousin, Alvaro de Portugal y Colón, Count of Gelves. He married Luis's daughter, Felipa, as a compromise (arranged by Luis) in the inheritance suit; they moved to Santo Domingo, returning to Spain four years later. Diego's death without heirs, as the last heir in the direct male line from Cristoforo, precipitated the second great inheritance lawsuit, which lasted until 1796.

the text in this section is copied from an article in Wikipedia

Diego Colón de Toledo y Pravia, 4th Admiral of the Indies (died 28 January 1578) was a paternal grandson of Diego Colón and his wife María de Toledo y Rojas, making him a great-grandson of Christopher Columbus.

He married his first cousin Felipa Colón de Toledo, 2nd Duchess of Veragua, the second daughter and heiress of Luis Colón de Toledo, 1st Duke of Veragua, and his first wife María de Mosquera y Pasamonte, without issue. He held the Almirante de las Índias office in her place, which she had inherited.

1. ↑ ^{1.0 1.1 1.2} Schoenrich, Otto. The Legacy of Christopher Columbus: Three Centuries of Disputes, Lawsuits, Struggles for Rewards and Inheritances, Brands by the Admiral of Aragón and Others, Spoliations by Sir Frances Drake and Others, Claims of Ilegitimates and Black Sheep, Resulting from the Discovery of America. (Glendale, California: A.H. Clark Co., 1949-50).
2.   Diego Colón de Toledo, 4th Admiral of the Indies, in Wikipedia: The Free Encyclopedia.