'Isabella, the eighth child of Samuel and Isabella (Sharon) Huston, on October 14, 1765, married James Clendenin, ... By him she had issue nine children, ...'
'Isabella Huston's first husband died while she was a young woman and she afterward married Nathaniel Eckels, a widower, who by his former marriage also had a family.
Isabella (Huston) (Clendenin) by Nathaniel Eckels, her second husband, had two sons, ...'
This information isn't consistent with a 1799 death date for James Clendenin (Find A Grave, but no grave marker) and a 1785 marriage date for Isabella and Nathaniel Eckels (FamilySearch Family Tree, no source citation). It isn't clear where the error lies.