Talcottville is a small community is southern Lewis County. It is also the seat for the Town of Leyden.
Talcottville has many interesting historical facts. It was the first settlement in Lewis county and its cemetery has the interred remains for that family. William Topping and his family settled in 1793 on what is now the northwest corner of State Rte. 12d and Domser Rd.
Active businesses in the hamlet include: Talcottville Cemetery Association, a division of Lewis County Monuments, Creekside Builders, Fox Crafts, and portions of three active dairy farms.
The author and critic Edmund Wilson was a summer resident, and wrote "Upstate: Records and Recollections of Northern New York" (New York: Farrar, Straus & Giroux, 1971; reprint, Syracuse: Syracuse University Press, 1990), a memoir of his time in Talcottville.