Garfield County is a county located in the U.S. state of Oklahoma named after President James A. Garfield. As of the 2010 census, the population was 60,580. Enid is the county seat and largest city within Garfield County.
Prior to the Land Run of 1893, Garfield County was named O County and was part of the Cherokee Outlet, occupied by the Cherokee people following the Treaty of New Echota and the Cherokee trail of tears. Historically, the area was a hunting ground for the Wichita, Osage, and Kiowa tribes.
The Chisholm Trail, stage coach lines, mail routes, and railroads passed through stations at Buffalo Springs and Skeleton, today known as Bison and Enid. Railroad development in the county began four years prior to the land opening. Enid became a central hub within the county. Historical railroads included Enid and Tonkawa Railway, Enid and Anadarko Railway, Blackwell, Enid and Southwestern Railway, Enid Central Railway and the Denver, Enid and Gulf Railroad.