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Laodice III (Greek: Λαοδίκη) also known as Laodika, was a princess of Pontus and a Seleucid queen. She was regent for her first born son, Antiochus, during the Anabase expedition of her husband, Antiochus III the Great, between 212 and 206 BC. Antiochus created a royal cult dedicated to her in 193 BC. In 192 BC she was pushed out of political life due to her husband's remarriage. Her last known activities are documented in 177–176 BC and relate to the court of her son, Seleucus IV.