Information from Ronald G. Meek.
There is a Mary Ann Pirtle, age 34, born KY, listed in the 1850 Rusk County, TX Census with children Thomas J., age 12, born KY; James Perry (Penny?), age 10, born KY; Rosella, age 5, born KY; Georgeana, age 2 mos, born KY. Living next to a Brown family.
Also, an A.J. Pirtle, age 34, born KY, listed in the 1850 Cherokee County, TX Census with wife Ann C., age 26, born SC; Children James, age 6, born AR; John M., age 4, born TX; Albert J., age 2, born TX; William C., age 1/12, born TX; and an Elsiak Patterson (Male), age 15, born GA.