No records have yet surfaced to connect Isabel with the Cambridge, MA family.
References
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WILL: Dated Oct 14, 1742; proved May 29, 1753. Children: Jane Clark, Edward, Rachel Saunders, Mercy Bliven granddaughter of son John, James. [Westerly Wills DAR roll #7, Seattle Public Library].
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Isabel Bliven of Westerly widow of Edward p. 361-2 & receipts p. 373-4. Sons: Edward, John whose daughter received & James Bliven who was exor -- for James' will (p.365-6); daughter-in-law Mercy Bliven; daughter Jane Clark who died bef July 6, 1753 (her son Ichabod Clark signed) & Rachel Saunders; granddaughter Mercy Bliven daughter of son John. Witnesses: John Dodge, Ebenezer Rathbun & George Stillman. [RIGR Vol 11, p. 157]
There is substantial circumstantial evidence that John Maccoon of Westerly and John Maccoon of Cambridge, MA were two different people.