Source:Shakespeare, Edward Oram. Pedigree of William McIntire Shakespear, Sr

Family tree of the author, Dr. Edward Oram Shakespeare, and his father William McIntire Shakespeare.

From New York Times, 2 Jun 1900:

Dr. Edward Oram Shakespeare of Philadelphia, one of the most prominent opthalmic surgeons in the United States, died suddenly yesterday in his room at the Hotel Walton, Philadelphia, of heart disease, with which he had been troubled for several years. During the war with Spain, Dr. Shakespeare was appointed a Brigade Surgeon, with the rank of Major of Volunteers, and at the time of his death he was acting as a member of the commission attached to the office of the Surgeon General at Washington to investigate the causes of typhoid fever in the United States Army.

Dr. Shakespeare was born in New Castle County, Delaware, May 19, 1846. Through his father, William M. Shakespeare of Dover, Del., he was descended from Edmund Shakespeare, a brother of the poet. Through his mother, Catherine Haman, he traced his descent to the Barons of Crevefuer and Cethan. He was graduated from Dickinson College in the 1867 and from the Medical Department of the University of Pennsylvania two years later. Dr. Shakespeare began the practice of his profession at Dover, Del., but in 1874 removed to Philadelphia where later he was appointed lecturer on operative opthalmic surgery in the University of Pennsylvania. He was, in 1885, sent as the representative of the Federal Government to Spain and other European countries in which cholera was prevalent, to investigate the cause, prevention, and cure of that disease. He spent several months abroad in the study of the subject, and made a report to Congress.

Dr. Shakespeare was a member of many scientific societies, including the Delaware Medical Society, the Northern Medical Society, the Pathological Society of Philadelphia, and the Philadelphia County Medical Society. He contributed to The American Journal of Medical Sciences for January, 1876, a paper on "A New Opthalmoscope and Opthalmometer, Devised for Clinical Use and for Physiological and Therapeutical Investigation on Men and Animals", which he had invented.

Also co-author of A System of Human Anatomy.