Place:Santa Maria Sopra Minerva, Roma, Roma, Lazio, Italy

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Santa Maria sopra Minerva is one of the major churches of the Roman Catholic Order of Preachers (better known as the Dominicans) in Rome, Italy. The church's name derives from the fact that the first Christian church structure on the site was built directly over the ruins or foundations of a temple dedicated to the Egyptian goddess Isis, which had been erroneously ascribed to the Greco-Roman goddess Minerva^[1] (possibly due to interpretatio romana).

The church is located in Piazza della Minerva one block behind the Pantheon in the Pigna rione of Rome within the ancient district known as the Campus Martius. The present church and disposition of surrounding structures is visible in a detail from the Nolli Map of 1748.

While many other medieval churches in Rome have been given Baroque makeovers that cover Gothic structures, the Minerva is the only extant example of original Gothic architecture church building in Rome. Behind a restrained Renaissance style façade the Gothic interior features arched vaulting that was painted blue with gilded stars and trimmed with brilliant red ribbing in a 19th-century Neo-Gothic restoration.

The church and adjoining convent served at various times throughout its history as the Dominican Order's headquarters. Today the headquarters have been re-established in their original location at the Roman convent of Santa Sabina. The titulus of was conferred on 28 June 2018 to Cardinal António Marto.