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New Florence is a city in Montgomery County, Missouri, United States. The population was 641 at the 2020 census. New Florence includes a branch of Stone Hill Winery, based in Hermann. From here to the St. Louis suburbs is the geographic area known as the Missouri Rhineland, first established as a center of vineyards by German immigrants in the mid-19th century. New Florence lies at the junction of Interstate 70 and State Highway 19. Highway 19 is accessible from Interstate 70 via Exit 175. [edit] Research Tips
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