Samuel Peirce, first-born child of Samuel Peirce (Thomas, Thomas) and Lydia (Bacon) Pierce, was born at Woburn, Massachusetts, 25 November 1681. He died 26 January 1773, presumably at Mansfield, Connecticut. He married at Woburn 14 June 1705, Abigail Johnson, born there 4 October 1674, daughter of Major William and Esther (Wiswall) Johnson. Abigail probably died before Samuel since she is not mentioned in his will.
The will of Samuel Peirce of Mansfield, dated 12 February 1767 and proved 14 February 1774, mentions son Samuel Peirce, son Josiah Peirce, daughter Abigail Wyman, daughter Esther Dimmock, granddaughter Esther "the Daughter of my son Sam'll," and sons Seth and Enoch.