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Maria Theresa of Austria (Maria Theresia Isabella; 31 July 1816 – 8 August 1867) was the second wife of Ferdinand II of the Two Sicilies, making her Queen of the Two-Sicilies. She was the eldest daughter of Archduke Charles, Duke of Teschen and Princess Henrietta of Nassau-Weilburg.
Her paternal grandparents were Leopold II, Holy Roman Emperor and Maria Luisa of Spain. Her maternal grandparents were Frederick William of Nassau-Weilburg and his wife Burgravine Louise Isabelle of Kirchberg.
Maria Theresa was Princess-Abbess of the Theresian Royal and Imperial Ladies Chapter of the Castle of Prague (1834–1835).