"He married three times:
:Firstly to Bridget Chichester, seventh daughter of Sir John Chichester (1519–1569) of Raleigh in the parish of Pilton, North Devon, a leading member of the Devonshire gentry, a naval captain, and ardent Protestant who served as Sheriff of Devon in 1550-1551, and as Knight of the Shire for Devon in 1547, April 1554, and 1563, and Member of Parliament for Barnstaple in 1559. By his first wife he had one son Timothy Prideaux (born 1590, baptised at Holsworthy), who predeceased his father, and three daughters.