Template:Wp-East Palestine, Ohio

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East Palestine is a village in eastern Columbiana County, Ohio, United States. The population was 4,761 at the 2020 census. Located on the state's border with Pennsylvania, East Palestine is 20 miles (31 km) south of Youngstown and 40 miles (64 km) northwest of Pittsburgh. It is a part of the Salem, Ohio micropolitan area.

East Palestine is located along the Norfolk Southern Railway, and has a freight train station. From the 1870s until the mid 1960s, East Palestine was home to a large industry in ceramics and tire manufacturing. Since then, it has relied on its close proximity to industries in the metropolitan areas of Youngstown and Pittsburgh.