Wezembeek-Oppem is a municipality in the Belgian province of Flemish Brabant, ten kilometres east of the centre of Brussels. The municipality only comprises the town of Wezembeek-Oppem proper. On January 1, 2006 Wezembeek-Oppem had a total population of 13,504. The total area is 6.82 km² which gives a population density of 1,980 inhabitants per km².
Wezembeek-Oppem is home to a large community of international expatriates, in part because of the presence of the Internationale Deutsche Schule Brüssel (iDSB) in Wezembeek-Oppem itself, and the British School in nearby Tervuren.