Tishomingo is named after the Chickasaw chief, who signed the Treaty of Pontotoc in 1832. He served with General Anthony Wayne against the Shawnees in the Northwest Territory and received a silver medal from President George Washington. During the War of 1812, he served under Andrew Jackson. After his service in the military, he retired to become a farmer until white settlers came onto his land. In 1837, a final treaty forced the Chickasaws to move to the Indian Territory in present-day Oklahoma. Tishomingo died of smallpox on the Trail of Tears and is buried in Arkansas somewhere near Little Rock . His son, Iuka, is the namesake of the county seat of Tishomingo County, Mississippi.
The jazz standard "Tishomingo Blues" is named after Tishomingo.
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