Tabora Region is one of Tanzania's 30 administrative regions. The regional capital is the municipality of Tabora. According to the 2012 national census, the region had a population of 2,291,623, which was lower than the pre-census projection of 2,539,715 . For 2002-2012, the region's 2.9 percent average annual population growth rate was the ninth highest in the country. It was also the 24th most densely populated region with 30 people per square kilometre. The region's average household size of 6.0 persons was the third highest in the country.
The region is in the central-western part of the country. With a size of , the region is slightly larger than Panama. Forest reserves cover (46 percent of the region), and game reserves cover (22 percent of the region). Most economic activity in the region is agricultural.
The regional commissioner of the region is Fatma Mwassa.