The village lies largely on the north side of the A6121 road from Uppingham to Stamford. It is divided into two by a small stream, the Foss, which is a tributary of the River Chater. South Luffenham Hall stands a short distance to the south-east of St Mary's church.
The village has two pubs, the Boot and Shoe and the Coach House (previously the Halfway House), as well as the church and village hall. The post office closed in April 2006, but re-opened (Monday afternoons only) in May of that year in the village hall. There is a ruined windmill near the outskirts of the village.
It once had a railway station that was located to the north of the village and also served the neighbouring village of North Luffenham. Luffenham railway station was opened in 1848 and closed in 1966. In fact there were two railway stations in the parish, since Morcott station lay just within the South Luffenham parish boundary.