Santa Rosa is a municipality in the Brazilian state of Rio Grande do Sul, located at latitude 27º52'15" and longitude 54º28'53" at a height of 277 meters above sea level. It has an area of 488.42 km². Its estimated population is 68 595 (2010). It is known as the "National Cradle of Soybean".
Santa Rosa was created as a colony of European immigrants in 1915, mainly Germans and Russians. The German dialect traditionally spoken in the region is Riograndenser Hunsrückisch.
The city is served by Luís Alberto Lehr Airport.