Saint James parish is located in the northeastern section of the island of Nevis and the parish capital is Newcastle, which is next to the Nevis airport. Not far east from Newcastle is the hotel Nisbet Plantation Beach Club, and the Newcastle Pottery. A small distance further east still is the Medical University of the Americas.
In terms of land area, Saint James is the largest parish in Saint Kitts and Nevis. However, it is also the least populated, as it mainly consisting of small communities separated by dry scrub. The villages in this parish include Newcastle, Rawlins, Mount Lily, Fountain, Camps, Burnaby, Hicks, Brick Kiln, Whitehall, and Butlers.
All the Nevis parishes were drawn up to include a segment of Nevis Peak itself, but this parish also includes a secondary peak at 1901 feet which is unnamed on the Ordnance Survey map, but which is locally known as Butler's peak. The parish also includes an ancient weathered volcanic core called Round Hill. The northern coast of Saint James Parish has several long sandy beaches: Lover's Beach, Newcastle Beach and Long Haul Bay. The more easterly part however is mostly rocky coast. Behind Butler's peak, there is flourishing rain forest.