Otisville is a village in Orange County, New York, in the United States. The population was 1,068 at the 2010 census. It is part of the Poughkeepsie–Newburgh–Middletown, NY Metropolitan Statistical Area as well as the larger New York–Newark–Bridgeport, NY-NJ-CT-PA Combined Statistical Area.
The village of Otisville is in the town of Mount Hope, located near the west town line.
The mayor of Otisville is Brian Wona.
The name "Otisville" also refers to Federal Correctional Institution, Otisville and Otisville Correctional Facility, a NY prison, both located nearby. There is also the station on Metro-North's Port Jervis Line.