Osterley lies north of the A4 (The Great West Road) and extends further northwards beyond the M4 Motorway. Syon Lane forms the border to the east, while the border with the town of Heston lies to the west.
Located within Osterley is the large ancestral private estate of Osterley Park (one of the largest open spaces in west London) and its mansion. These were formerly owned by the Jersey family and were used during World War II as the home for Tom Wintringham's Home Guard training school. They are now National Trust property. During the inter-war period of the 1930s when the Great West Road was completed ribbon development housing appeared, and this gradually expanded to form the comparatively small residential sections within Osterley.
Besides Osterley House and Park, the district is also known for embracing one of the London residences of The Sultan of Brunei (The Aviary Farm in Windmill Lane).
The electoral ward of Osterley and Spring Grove now has its own dedicated Police team as part of the Metropolitan Police Safer Neighbourhoods programme.