Louisville is a town in St. Lawrence County, New York, United States. The population was 3,145 at the 2010 census. The town is reportedly named after a French king, but it is pronounced as "Lewis-ville."
The Town of Louisville is at the north border of the county and is west of Village of Massena.
The town was first settled around 1800.
The town was established in 1810 from part of the Town of Massena. Almost half of Louisville was lost to form the Town of Norfolk in 1823. Part of the lost territory was returned from the Town of Norfolk in 1844. An attempt to take part of Louisville for the Town of Massena in 1849 was rejected.