Guyzance, historically Guizance, is a small village or hamlet in Northumberland, England. It is located south east of Alnwick on the River Coquet, several miles west of its mouth. Guyzance is one of only two places in Great Britain with a -zance ending; the other is Penzance in Cornwall. The similar names are co-incidence however.
The name Guyzance is thought to be derived from a Norman family name "Guines", from an area of the same name near Calais. Other forms of the name recorded locally include "Gynis" (1242), "Gysnes" and "Gisyng".
In 1885, Guyzance was described thus in Whellan's History, Topography, and Directory of Northumberland:
"GUYZANCE, or GUYSON, is a township and village in this Shilbottle parish, the property of the Duke of Northumberland; Robert Delisle, Esq. the heirs of the late Thomas Fenwick, Esq., and Thomas Tate, Esq. The rateable value is £l,671 10s., and the tithes, which are the properly of Thomas Tate, Esq., are valued at £130 per annum. The number of inhabitants in 1801, was 172; in 1811, 186; in 1821, 173; in 1831, 197; in 184l, 205; and in 1851, 213 souls. THE VILLAGE of Guyzance is situated seven miles south by east of Alnwick. There was formerly a priory here, which was annexed to Alnwick Abbey, by Eustace Fitz John. We find from Tanner's Monastica that it was endowed with a portion of the tithes, and two bovates of land, but as to any other portion of its history we possess no records. The remains of the old chapel are still here, with the burying ground, in which the Tate family are still interred. BANK HOUSE, the seat of Thomas Tate, Esq., is situated about a mile north of the village."