Syresham is a village and civil parish in the South Northamptonshire District in Northamptonshire, England. It is near the town of Brackley and close to the Silverstone Motor Racing Circuit. It is surrounded by villages and hamlets such as Whitfield, Helmdon, Silverstone and Wappenham in Northamptonshire and Biddlesden in Buckinghamshire. The border with Buckinghamshire lies just to the south of the village. The border itself is defined by the River Great Ouse, which rises within the parish. There are two small hamlets in the parish: Crowfield and Pimlico.
The local geology includes the cornbrash and oolitic limestone of Jurassic age. There is a large abandoned quarry north of the church which supplied the stone for many of the older buildings in the village. The population, like so many other villages in England, is now much lower than even a century ago due to the British agricultural revolution. There are the remains of a very large fish pond south of the church and close to the manor house. The dam wall still stands but the pond was drained long ago for its rich pasture.
There are several deserted medieval villages nearby, including Astwell near Helmdon, the site of the still-standing keep or gatehouse of Astwell Castle.