Clymer is a town in Chautauqua County, New York, United States. The population was 1,698 at the 2010 census. The town is named for George Clymer, a signer of the Declaration of Independence. Clymer is located in the southwest part of the county.
Settlement began around 1820. The town of Clymer was established in 1829 from a division of the town of Chautauqua. In 1821, a division of Clymer was made to form the new town of Mina and again in 1829 to form the town of French Creek. In 1915, the population of Clymer was 1,341.
Neckers Co., a general store, has occupied the northwest corner of the main intersection in town since 1910, passing through four generations of the Neckers family.
On or about September 24, 2012, Clymer Central School superintendent Keith Reed Jr. was shot to death by an apparent murderer on his property near Clymer.