Carlisle is a village located in the southwestern part of the U.S. state of Ohio in northwestern Warren and southern Montgomery counties. As of the 2010 census, the village's population was 4,915, down from 5,121 in the 2000 census. This population loss caused Carlisle to once again become a village. (Carlisle had become a city after the 2000 census, as its population had increased from 4,872 in 1990.) The village is in Franklin Township, Warren County, Ohio and German Township, Montgomery County, Ohio.
The Warren County portion of Carlisle is part of the Cincinnati–Middletown, OH-KY-IN Metropolitan Statistical Area, while the Montgomery County portion is part of the Dayton, OH Metropolitan Statistical Area.
Carlisle is named for "railroad man" George B. Carlisle, who in the mid-19th century "bought and platted a large section of the community".
Carlisle is known for an area landmark: a "double UFO" house off Chamberlain Road, which resembles two silver-colored flying saucers connected by a metal duct. This is actually two Futuro houses combined into one residence.