Biggenden is a town situated on the Isis Highway in southern Queensland, Australia, 339 km north-west of the state capital Brisbane, and 84 km west of Maryborough. At the 2006 census, Biggenden had a population of 644.
Primary production is the most significant industry in the Shire with beef and dairy cattle being predominant. Other agricultural pursuits include grain crops, piggeries, peanuts, citrus and timber. The area is also rich in minerals. Biggenden Mine is located eight kilometres out of town off Ban Ban Springs Road. Gold, bismuth and more recently magnetite have been extracted from the mine. The township is also close to Coalstoun Lakes National Park and Mount Walsh National Park.
Biggenden was founded in 1889 as a service centre to the short-lived goldrush towns of Paradise and Shamrock; and for coach passengers travelling west from Maryborough. The township, including the intriguingly named Live And Let Live Inn, moved to a new location alongside the railway station when the rail line arrived in 1891.