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Demetrius II (Dēmḗtrios B; died 125 BC), called Nicator (Nikátōr, "Victor"), was one of the sons of Demetrius I Soter. His mother may have been Laodice V, as was the case with his brother Antiochus VII Sidetes. Demetrius ruled the Seleucid Empire for two periods, separated by a number of years of captivity in Hyrcania in Parthia, first from September 145 BC to July/August 138 BC, and again from 129 BC until his death in 125 BC. His brother Antiochus VII ruled the Seleucid Empire in the interim between his two reigns.
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