On September 22, 1851, our subject married Miss Jennie Rankin, at Cynthiana, a good and noble woman, who preceded him to the grave only a few years. To them were born Harry, Robert and Fannie, all of whom reside in Tuscola, the two former composing the large clothing house of Harry Madison & Company. In 1854 Mr. and Mrs. Madison came to Charleston, Illinois, where he opened up a store, and in 1860 they removed to Tuscola, where Mr. Madison engaged in the mercantile business, which he continued up to within two years of his death.